The scientist tried to isolate one cause of the change.
What does Isolate mean?
Isolate means to separate from others.
Dictionary definition
to separate someone or something from others.
Isolate in a sentence
The teacher asked students to isolate the main idea in the paragraph.
When solving a problem, it can help to isolate one variable at a time.
Ready to write your own? Study the examples, then practice isolate in a sentence with Sentence Builder checklist feedback.
Practice the meaning of Isolate
Answer three quick questions about its meaning and related words.
What does isolate mean?
Isolate means separate or set apart.
Which sentence uses isolate correctly?
A detail can be separated from others for closer study.
Which word is an antonym of isolate?
Combine means put together, the opposite of isolate.
Nice work!
You completed 3 questions.
Isolate
Voice settings
eye · suh · layt · strongest beat: eye
3 syllables. Say each part, then blend the word.
- Syllables
- eye · suh · layt
- Strongest beat
- eye
- Ending
- layt
- Tip
- Put a little extra energy on eye.
Say Isolate
Record a short attempt, then compare it with the Coach. Your recording stays on this device and is not uploaded.
Ready when you are.
Words like Isolate
Opposite words
Want to practice isolate synonyms in context? Try a Synonym Search question like "Leaving one player out can alienate a teammate," then compare close word choices. Practice isolate synonyms.
Isolate word family
isolate
isolated
Separated from others.
isolating
Separating from others.
isolation
The state of being separated.
Explore related words
Understand Isolate
Isolate means to separate from others.
Isolate is not the same as combine. Isolate means isolate means to separate from others.
Read this model sentence: The teacher asked students to isolate the main idea in the paragraph. Clue words: teacher, asked, students. Underline clue words that show why isolate fits instead of combine. Now write one new sentence that shows isolate without using the word isolate. Ask: Does my sentence clearly show isolate?
Ask students to explain this model sentence: "The teacher asked students to isolate the main idea in the paragraph." Why does isolate fit better than combine?
Practice Isolate and explore more word games
Cards labelled “Practice ISOLATE” keep this word in focus. Explore cards open games with other words.

Sentence Builder
Write your own sentence with this word and revise with checklist feedback.
Write a sentence with ISOLATE
Spell Hive
Hear the word, type the spelling, and use spoken clues when needed.
Practice spelling
Define the Word Hive
Choose the meaning that fits and get instant feedback.
Practice definitions
Vocabulary Match
Pair words with meanings and review misses with dictionary links.
Match meanings
Context Clue Challenge
Use sentence clues to choose the word that fits the meaning.
Use context clues
Synonym Search
Compare meanings in a question that includes ISOLATE.
Practice ISOLATE
Scrambled Bees
Rebuild words from mixed-up letters for spelling practice.
Rebuild words